Improving tumor accumulation with SPIO-Loaded acoustic nanodroplets and magnetic targeting

Abstract

Acoustic droplet vaporization (ADV) provides mechanical and chemical effects in tumor theranostic applications. Nano-sized droplets (NDs) could increase drug accumulation within tumor through the enhanced permeability and retention (EPR) effect. However, the high interstitial fluid pressure in solid tumor would resist NDs extravasation. In order to overcome… (More)

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