Improving the preclinical models for the study of chemotherapy-induced cardiotoxicity: a Position Paper of the Italian Working Group on Drug Cardiotoxicity and Cardioprotection

@article{Madonna2015ImprovingTP,
  title={Improving the preclinical models for the study of chemotherapy-induced cardiotoxicity: a Position Paper of the Italian Working Group on Drug Cardiotoxicity and Cardioprotection},
  author={Rosalinda Madonna and Christian Cadeddu and Martino Deidda and Donato Mele and Ines Monte and Giuseppina Novo and Pasquale Pagliaro and Alessia Pepe and Paolo Spallarossa and Carlo Gabriele Tocchetti and Concetta Zito and Giuseppe Mercuro},
  journal={Heart Failure Reviews},
  year={2015},
  volume={20},
  pages={621-631}
}
  • Rosalinda Madonna, Christian Cadeddu, +9 authors Giuseppe Mercuro
  • Published 2015
  • Medicine
  • Heart Failure Reviews
  • AbstractAlthough treatment for heart failure induced by cancer therapy has improved in recent years, the prevalence of cardiomyopathy due to antineoplastic therapy remains significant worldwide. In addition to traditional mediators of myocardial damage, such as reactive oxygen species, new pathways and target cells should be considered responsible for the impairment of cardiac function during anticancer treatment. Accordingly, there is a need to develop novel therapeutic strategies to protect… CONTINUE READING

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