Improving solubility and pharmacokinetics of meloxicam via multiple-component crystal formation.

Abstract

Meloxicam is a nonsteroidal anti-inflammatory drug prescribed for rheumatoid arthritis, osteoarthritis, postoperative pain and fever. Meloxicam exhibits low solubility in acidic aqueous media and a slow onset of action in biological subjects. An oral dosage form of meloxicam with enhanced aqueous solubility is desired to enable a faster onset of action and… (More)
DOI: 10.1021/mp300169c

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