Improving solubility and chemical stability of natural compounds for medicinal use by incorporation into liposomes.

@article{Coimbra2011ImprovingSA,
  title={Improving solubility and chemical stability of natural compounds for medicinal use by incorporation into liposomes.},
  author={Maria J Coimbra and Benedetta Isacchi and Louis van Bloois and Javier Tora{\~n}o and Aldo Ket and Xiaojie Wu and Femke Broere and Josbert M. Metselaar and Cristianne J.F. Rijcken and Gert Storm and Rita Bilia and Raymond Schiffelers},
  journal={International journal of pharmaceutics},
  year={2011},
  volume={416 2},
  pages={433-42}
}
Natural bioactive compounds have been studied for a long time for their chemopreventive and therapeutic potential in several chronic inflammatory diseases, including cancer. However, their physicochemical properties generally result in poor chemical stability and lack of in vivo bioavailability. Very few human clinical trials have addressed absorption… CONTINUE READING