Improving disease gene prioritization using the semantic similarity of Gene Ontology terms

Abstract

MOTIVATION Many hereditary human diseases are polygenic, resulting from sequence alterations in multiple genes. Genomic linkage and association studies are commonly performed for identifying disease-related genes. Such studies often yield lists of up to several hundred candidate genes, which have to be prioritized and validated further. Recent studies… (More)
DOI: 10.1093/bioinformatics/btq384

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@inproceedings{Schlicker2010ImprovingDG, title={Improving disease gene prioritization using the semantic similarity of Gene Ontology terms}, author={Andreas Schlicker and Thomas Lengauer and Mario Albrecht}, booktitle={Bioinformatics}, year={2010} }