Improving clinical outcomes from acute subdural hematomas with the emergency preoperative administration of high doses of mannitol: a randomized trial.

OBJECTIVE To evaluate clinical outcomes and postoperative physiological findings for comatose patients with acute subdural hematomas who received preoperative high-dose mannitol (HDM) versus conventional-dose mannitol treatment. METHODS One hundred seventy-eight adult patients with non-missile, traumatic, acute, subdural hematomas were prospectively and… CONTINUE READING