Improving bone marrow stromal cell attachment on chitosan/hydroxyapatite scaffolds by an immobilized RGD peptide.

@article{Qu2010ImprovingBM,
  title={Improving bone marrow stromal cell attachment on chitosan/hydroxyapatite scaffolds by an immobilized RGD peptide.},
  author={Zhiwei Qu and Jinglong Yan and Baoqiang Li and Jinpeng Zhuang and Yanming Huang},
  journal={Biomedical materials},
  year={2010},
  volume={5 6},
  pages={065001}
}
Ample cell adhesion to scaffolds is essential for effective bone tissue engineering. Chitosan/hydroxyapatite (CS/HA) scaffolds with channel-shaped and spherically shaped pore morphologies were prepared via in situ compositing hybridization in combination with lyophilization. The sizes of channel-shaped and spherically shaped pores of the CS/HA scaffolds were 150-650 µm and 3-15 µm, respectively. The RGD peptide (Arg-Gly-Asp) was bound to the surface of CS/HA scaffolds via physical adsorption… CONTINUE READING

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