Improving body composition and physical activity in Prader-Willi Syndrome.

@article{Eiholzer2003ImprovingBC,
  title={Improving body composition and physical activity in Prader-Willi Syndrome.},
  author={Urs Eiholzer and Yves Nordmann and Dagmar L'Allemand and Michael Schlumpf and Silvia Schmid and Katrin Kromeyer-Hauschild},
  journal={The Journal of pediatrics},
  year={2003},
  volume={142 1},
  pages={
          73-8
        }
}
OBJECTIVE To determine if muscle training in Prader-Willi Syndrome (PWS) can improve local body composition, physical capacity, and activity. STUDY DESIGN Seventeen children and adolescents with PWS and 18 control children were enrolled in a daily short calf muscle training program for 3 months. Before (t(0)) and after 3 months of training (t(3m)), spontaneous physical activity and exercise capacity were assessed by pedometer registrations and activity protocols. Local body composition was… 
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Everyday Physical Activity and Adiposity in Prader-Willi Syndrome
TLDR
The results indicate that, as a group, children with PWS have an inactive lifestyle, but they cannot be stereotyped as inactive since half of them had normal activity levels.
Effectiveness of a 6-month home-based training program in Prader-Willi patients.
Increasing physical activity in adult women with Prader-Willi syndrome: A transferability study.
TLDR
Supervised home-based exercise sessions are an effective strategy to improve PA in women with Prader-Willi syndrome who are less active than women matched for adiposity.
Growth hormone improves mobility and body composition in infants and toddlers with Prader-Willi syndrome.
Assessment of physical function in adults with Prader-Willi syndrome
TLDR
Repeated rising from a chair and 10 m walk are useful assessments in clinical practice to identify adults with Prader-Willi syndrome with reduced physical function, emphasising the importance of efforts to keep normal body weight and body composition in adults with PWS.
Growth hormone and body composition in children younger than 2 years with Prader-Willi syndrome.
Association between foot growth and musculoskeletal loading in children with Prader-Willi syndrome before and during growth hormone treatment.
Physical Activity in Patients with Prader-Willi Syndrome—A Systematic Review of Observational and Interventional Studies
TLDR
In conclusion, supervised PA programs are beneficial for children and adults with PWS and support should be provided to families to facilitate their implementation in real-life settings.
Growth Hormone Therapy, Muscle Thickness, and Motor Development in Prader-Willi Syndrome: An RCT
TLDR
GH increased muscle thickness, which was related to muscle strength and motor development in infants with Prader-Willi syndrome, which suggests a training effect.
Myokine levels after resistance exercise in young adults with Prader–Willi syndrome (PWS)
TLDR
The results suggest that PWS young adults are capable of performing resistance/strength‐building exercise and the lower CK and peak lactate levels in PWS may reflect decreased muscle mass in this population.
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References

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TLDR
Exogenous GH changes the phenotype of children with PWS: fat mass becomes normal, but, at least in the setting studied, GH is not sufficient to normalize lean tissue mass.
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TLDR
PWS patients showed a peculiar body composition, to some extent similar to that found in subjects deficient in growth hormone or even to sedentary and elderly people, which suggests the importance of an accurate analysis of body composition in PWS patients.
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TLDR
Activity related energy expenditure is decreased in Prader–Willi syndrome compared with controls adjusted for bone age, FM and gender.
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TLDR
In children and adolescents with PWS, adiposity is associated with a reduced fat-free mass and extracellular-to-intracllular-water ratio is increased, both findings are related to GH function and physical activity.
Energy expenditure and body composition in Prader-Willi syndrome
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TLDR
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TLDR
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TLDR
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TLDR
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