Corpus ID: 13421726

Improving anti-drug antibody assay performance in Gyrolab for therapeutic recombinant antibody Infliximab

@inproceedings{LiUIKEEX2014ImprovingAA,
  title={Improving anti-drug antibody assay performance in Gyrolab for therapeutic recombinant antibody Infliximab},
  author={LiU-IKE-EX},
  year={2014}
}
  • LiU-IKE-EX
  • Published 2014
  • Chemistry
  • Monoclonal antibodies can be used as targeting therapies for several diseases. One major concern when using these therapies is anti-drug antibodies which may hamper the drugs efficiency. Gyrolab is an automated platform which can be used to develop bridging immunoassays where the anti-drug antibodies affinity towards the monoclonal antibody is utilized. Anti-drug antibody immunoassay development on Gyrolab is limited mainly by three factors which may inappropriately affect signal intensity… CONTINUE READING

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