Improving Metabolic Health in Obese Male Mice via Diet and Exercise Restores Embryo Development and Fetal Growth

@inproceedings{McPherson2013ImprovingMH,
  title={Improving Metabolic Health in Obese Male Mice via Diet and Exercise Restores Embryo Development and Fetal Growth},
  author={Nicole O. McPherson and Hassan W. Bakos and Julie A Owens and Brian P. Setchell and Michelle T Lane},
  booktitle={PloS one},
  year={2013}
}
Paternal obesity is now clearly associated with or causal of impaired embryo and fetal development and reduced pregnancy rates in humans and rodents. This appears to be a result of reduced blastocyst potential. Whether these adverse embryo and fetal outcomes can be ameliorated by interventions to reduce paternal obesity has not been established. Here, male mice fed a high fat diet (HFD) to induce obesity were used, to determine if early embryo and fetal development is improved by interventions… CONTINUE READING
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