Improvements in vascular health by a low-fat diet, but not a high-fat diet, are mediated by changes in adipocyte biology

@inproceedings{Varady2011ImprovementsIV,
  title={Improvements in vascular health by a low-fat diet, but not a high-fat diet, are mediated by changes in adipocyte biology},
  author={Krista A. Varady and Surabhi Bhutani and Monica C. Klempel and Shane A Phillips},
  booktitle={Nutrition journal},
  year={2011}
}
BACKGROUND Low-fat (LF) and high-fat (HF) weight loss diets improve brachial artery flow-mediated dilation (FMD) in obese individuals, although results are conflicting. Moreover, the role that adipose tissue plays in mediating these diet-related effects are unknown. OBJECTIVE This study examined how modulations in FMD by HF and LF diets relate to changes in adipocyte parameters. DESIGN Obese subjects (n = 17) were randomized to a HF diet (60% kcal as fat) or a LF diet (25% kcal as fat) for… CONTINUE READING
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