Improvements in human sperm quality by long-term in vitro co-culture with isolated porcine Sertoli cells.

BACKGROUND Spermatogenesis is a complex process where spermatogonial germ cells become spermatozoa with the indispensable support of Sertoli cells (SCs), which provide 'ad hoc' structural and nutritional support. Unfortunately, for most sperm dysfunctions, no therapies are yet available except assisted reproductive technologies (ART) that are based on the… CONTINUE READING