Improvement of the clinical applicability of the Genomic Grade Index through a qRT-PCR test performed on frozen and formalin-fixed paraffin-embedded tissues

@article{Toussaint2009ImprovementOT,
  title={Improvement of the clinical applicability of the Genomic Grade Index through a qRT-PCR test performed on frozen and formalin-fixed paraffin-embedded tissues},
  author={J{\'e}r{\^o}me Toussaint and Anieta M. Sieuwerts and Benjamin Haibe-Kains and Christine Desmedt and Ghizlane Rouas and Adrian L. Harris and Denis P Larsimont and Martine J. Piccart and John A. Foekens and Virginie Durbecq and Christos Sotiriou},
  journal={BMC Genomics},
  year={2009},
  volume={10},
  pages={424 - 424}
}
Proliferation and tumor differentiation captured by the genomic grade index (GGI) are important prognostic indicators in breast cancer (BC) especially for the estrogen receptor positive (ER+) disease. The aims of this study were to convert this microarray index to a qRT-PCR assay (PCR-GGI), which could be realized on formalin fixed paraffin embedded samples (FFPE), and to assess its prognostic performance and predictive value of clinical benefit in early and advanced ER+ BC patients treated… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 30 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 21 REFERENCES

Similar Papers

Loading similar papers…