Improvement of the chronic lymphocytic leukemia scoring system with the monoclonal antibody SN8 (CD79b).

@article{Moreau1997ImprovementOT,
  title={Improvement of the chronic lymphocytic leukemia scoring system with the monoclonal antibody SN8 (CD79b).},
  author={Eglantine Moreau and Estela Matutes and Roger P. A’Hern and Alison Morilla and Ricardo M Morilla and Kwasi Owusu‐Ankomah and Ben K. Seon and Daniel Catovsky},
  journal={American journal of clinical pathology},
  year={1997},
  volume={108 4},
  pages={
          378-82
        }
}
A scoring system, based on the immunophenotypic analysis of a panel of five membrane markers (CD5, CD22, CD23, FMC7, SmIg) was shown to be useful in the distinction between chronic lymphocytic leukemia (CLL) and other B-cell lymphoproliferative diseases (non-CLL). We investigated whether the monoclonal antibody SN8 (CD79b) could improve our previous scoring system. Peripheral blood samples of 298 patients with CLL and 166 patients with non-CLL were analyzed by flow cytometry. Using the five… 
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