Improvement of symptoms in infant colic following reduction of lactose load with lactase.

  title={Improvement of symptoms in infant colic following reduction of lactose load with lactase.},
  author={Dipak J Kanabar and Manjit Randhawa and Paul Clayton},
  journal={Journal of human nutrition and dietetics : the official journal of the British Dietetic Association},
  volume={14 5},
  • D. Kanabar, M. Randhawa, P. Clayton
  • Published 1 October 2001
  • Medicine
  • Journal of human nutrition and dietetics : the official journal of the British Dietetic Association
Transient lactose intolerance has been identified as a possible causative factor in infant colic. A double-blind randomised placebo-controlled crossover study to investigate this has been undertaken in 53 babies with symptoms of colic. Pre-incubation of the feed with lactase resulted in breath hydrogen levels and total crying time which were both at least 45% lower than figures with placebo treatment, in 26% of the full trial group (95% confidence interval 12.9% to 44.4%), and in 38% of… 

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