Improvement of spatial cognition with dietary docosahexaenoic acid is associated with an increase in Fos expression in rat CA1 hippocampus.

@article{Tanabe2004ImprovementOS,
  title={Improvement of spatial cognition with dietary docosahexaenoic acid is associated with an increase in Fos expression in rat CA1 hippocampus.},
  author={Yoko Tanabe and Michio Hashimoto and Kozo Sugioka and Megumi Maruyama and Yoshimi Fujii and Rika Hagiwara and Toshiko Hara and Shahdat Md Hossain and Osamu Shido},
  journal={Clinical and experimental pharmacology & physiology},
  year={2004},
  volume={31 10},
  pages={700-3}
}
Twenty 5-week-old male Wistar rats were divided into two groups: one group was fed a fish oil-deficient diet and the other group was fed the same diet supplemented with per orally administered docosahexaenoic acid (DHA) for 12 weeks. Six weeks after the start of the administration of DHA, rats were trained for 6 weeks to acquire a reward at the end of each of four arms of an eight-arm radial maze. On completion of the radial maze task, the Fos expression in the hippocampus was examined… CONTINUE READING

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