Improvement of sensitivity to tamoxifen in estrogen receptor-positive and Herceptin-resistant breast cancer cells.

@article{Chen2008ImprovementOS,
  title={Improvement of sensitivity to tamoxifen in estrogen receptor-positive and Herceptin-resistant breast cancer cells.},
  author={Bin Chen and Yuanzhong Wang and Susan E. Kane and Shiuan W Chen},
  journal={Journal of molecular endocrinology},
  year={2008},
  volume={41 5},
  pages={367-77}
}
ERBB2 overexpression in estrogen receptor (ER)-positive breast cancer cells such as BT474 (BT) cells has been found to confer resistance to tamoxifen, and suppression of ERBB2 improves the antiproliferative effects of tamoxifen. In this study, the responsiveness to tamoxifen in the BT/HerR, Herceptin-resistant BT cell lines established through constant Herceptin exposure, was evaluated. Compared with BT cells, improvement of sensitivity to tamoxifen in BT/HerR was demonstrated by ER functional… CONTINUE READING
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Transmission of human immunode fi ciency virus and hepatitis C virus through

  • CK Kwan, T Al-Samarrai, LC Smith
  • liver transplantation
  • 2008

Blood , money and AIDS : Hemophiliacs are split ; liability cases bogged down in disputes

  • HT Kuo, X Ye, MS Sampaio
  • The New York Times , 11 Jun
  • 1996

Rabbi okays HIV - positive organ donation . Ynet , 6 May 2013

  • RJ Simonds, SD Holmberg, RL Hurwitz

The state of chronic kidney disease , ESRD , and morbidity and mortality in the fi rst year of dialysis

  • MA Lampe, DK Smith, GJ Anderson
  • Clin J Am Soc Nephrol

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