Improvement of mild hypoinsulinaemic diabetes in the rat by low non-toxic doses of vanadate.

Abstract

To exert their anti-diabetic effects in animals with overt alterations of glucose homeostasis, vanadium salts must be administered in high doses, which also cause decreases in food intake and body weight gain. In this study, we evaluated the effect of low doses of vanadate in rats made mildly diabetic (fed plasma glucose levels approximately 11 mmol/l) and… (More)

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