Improvement of leucocyte functions in ovariectomised aged rats after treatment with growth hormone, melatonin, oestrogens or phyto-oestrogens.

@article{Baeza2009ImprovementOL,
  title={Improvement of leucocyte functions in ovariectomised aged rats after treatment with growth hormone, melatonin, oestrogens or phyto-oestrogens.},
  author={Isabel Baeza and Carmen Alvarado and Pedro I Alvarez and Ver{\'o}nica Salazar and Carmen Castillo and Carmen Ariznavarreta and Jes{\'u}s Fdez-Tresguerres and M{\'o}nica de la Fuente},
  journal={Journal of reproductive immunology},
  year={2009},
  volume={80 1-2},
  pages={70-9}
}
Ageing is accompanied by an impairment of the physiological activity of the nervous, endocrine and immune system, as well as in neuroendocrine-immune communication. However, age-related changes in this communication axis have been scarcely studied. In mammals, the process of ageing is associated with an important decline in the secretion of several hormones, such as growth hormone (GH), melatonin (MEL) and oestrogens (Os). Ovariectomy, a model of menopause in rats, has been found to lead to… CONTINUE READING