Improvement of cardiac function during enzyme replacement therapy in patients with Fabry disease: a prospective strain rate imaging study.

@article{Weidemann2003ImprovementOC,
  title={Improvement of cardiac function during enzyme replacement therapy in patients with Fabry disease: a prospective strain rate imaging study.},
  author={Frank Weidemann and Frank Breunig and Meinrad Joachim Beer and Joern J. W. Sandstede and Oliver Turschner and Wolfram V{\"o}lker and Georg Ertl and Anita Knoll and Christoph Wanner and Joerg M. Strotmann},
  journal={Circulation},
  year={2003},
  volume={108 11},
  pages={
          1299-301
        }
}
BACKGROUND Enzyme replacement therapy (ERT) has been shown to enhance microvascular endothelial globotriaosylceramide clearance in the hearts of patients with Fabry disease. Whether these results can be translated into an improvement of myocardial function has yet to be demonstrated. METHODS AND RESULTS Sixteen patients with Fabry disease who were treated in an open-label study with 1.0 mg/kg body weight of recombinant alpha-Gal A (agalsidase beta, Fabrazyme) were followed up for 12 months… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 162 CITATIONS, ESTIMATED 47% COVERAGE

Fabry disease: a review of current management strategies.

  • QJM : monthly journal of the Association of Physicians
  • 2010
VIEW 9 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Echocardiographic Assessment of Patients with Fabry Disease.

  • Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
  • 2018

FILTER CITATIONS BY YEAR

2003
2018

CITATION STATISTICS

  • 6 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 11 REFERENCES

Early detection of Fabry cardiomyopathy by tissue Doppler imaging

M Pieroni, C Chimenti, R Ricci
  • Circulation
  • 2003

Real-time strain rate imaging of the left ventricle by ultrasound.

  • Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
  • 1998

Similar Papers

Loading similar papers…