Improvement of a Baculovirus Pesticide by Deletion of the EGT Gene

@article{OReilly1991ImprovementOA,
  title={Improvement of a Baculovirus Pesticide by Deletion of the EGT Gene},
  author={Declan. O'Reilly and Luitpold Miller},
  journal={Bio/Technology},
  year={1991},
  volume={9},
  pages={1086-1089}
}
The egt gene of the insect baculovirus Autographa californica nuclear polyhedrosis virus (AcMNPV) encodes the enzyme ecdysteroid UDP–glucosyltransferase. Expression of egt enables the virus to inhibit molting of its infected host. In this study, we have compared the growth and development of insects infected by viruses with and without a functional egt gene. Our data reveal that, since insects normally stop feeding for both larval–larval and larval–pupal molts, expression of egt prevents the… CONTINUE READING

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