Improvement of Pyoderma gangrenosum and psoriasis associated with Crohn disease with anti-tumor necrosis factor alpha monoclonal antibody.

@article{Tan2001ImprovementOP,
  title={Improvement of Pyoderma gangrenosum and psoriasis associated with Crohn disease with anti-tumor necrosis factor alpha monoclonal antibody.},
  author={M H Tan and Marsha Gordon and O. Lebwohl and Joshy George and Mark G. Lebwohl},
  journal={Archives of dermatology},
  year={2001},
  volume={137 7},
  pages={930-3}
}
BACKGROUND Infliximab is an anti-tumor necrosis factor alpha monoclonal antibody IgG effective in the treatment and maintenance of remission of active refractory Crohn disease and associated draining enterocutaneous fistulae. Multiple infusions of infliximab show promising results in patients with rheumatoid arthritis. Currently, there is limited clinical experience with infliximab, and no published reports exist on its use in cutaneous disorders. OBSERVATIONS We describe 2 patients with… CONTINUE READING

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