Improvement of Insulin-Induced Glucose Disposal in Obese Patients With NIDDM After 1-Wk Treatment With d-Fenfluramine

@article{Scheen1991ImprovementOI,
  title={Improvement of Insulin-Induced Glucose Disposal in Obese Patients With NIDDM After 1-Wk Treatment With d-Fenfluramine},
  author={A. Scheen and G. Paolisso and T. Salvatore and P. Lef{\`e}bvre},
  journal={Diabetes Care},
  year={1991},
  volume={14},
  pages={325 - 332}
}
  • A. Scheen, G. Paolisso, +1 author P. Lefèbvre
  • Published 1991
  • Medicine
  • Diabetes Care
  • Objective To study the short-term effects of the serotoninergic anorectic drug d-fenfluramine on insulininduced glucose disposal. Research Design and Methods A randomized double-blind placebocontrolled crossover trial with 1-wk treatment periods (2 × 15 mg/day d-fenfluramine) was conducted. Twenty obese subjects, 10 with normal oral glucose tolerance and 10 with non-insulin-dependent diabetes mellitus (NIDDM), were all treated with a weight-maintaining diet. Euglycemic-hyperinsulinemic glucose… CONTINUE READING
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    References

    SHOWING 1-10 OF 33 REFERENCES
    Effect of d-Fenfluramine on Basal Glucose Turnover and Fat-Feeding-Induced Insulin Resistance in Rats
    • 24
    • Highly Influential
    The effect of a low-calorie diet with and without fenfluramine on the glucose tolerance and insulin secretion of obese maturity-onset diabetics
    • J. Dykes
    • Medicine
    • Postgraduate medical journal
    • 1973
    • 22
    • PDF
    Fenfluramine in the treatment of non-insulin-dependent diabetics: hypoglycemic versus anorectic effect.
    • 31
    Actions of fenfluramine on glucose uptake in vitro and in vivo.
    • 13
    Hypoglycemic Action of Fenfluramine in Diabetes Mellitus
    • 56
    • Highly Influential