Improvement in liver pathology after 4 months of D-penicillamine in 5 doberman pinschers with subclinical hepatitis.

@article{Mandigers2005ImprovementIL,
  title={Improvement in liver pathology after 4 months of D-penicillamine in 5 doberman pinschers with subclinical hepatitis.},
  author={Paul J J Mandigers and Ted S. G. A. M. van den Ingh and Peter Bode and Jan Rothuizen},
  journal={Journal of veterinary internal medicine},
  year={2005},
  volume={19 1},
  pages={40-3}
}
Five female Doberman Pinschers with increased hepatic copper concentrations and persistent (3-4 years) subclinical hepatitis were treated with D-penicillamine for 4 months. Before and after treatment, the dogs underwent clinical, hematologic (red blood cell, white blood cell, and differential and thrombocyte counts), and clinical chemistry (creatinine, alkaline phosphatase, alanine aminotransferase, and total bile acid concentrations) examinations, and liver biopsies were examined… CONTINUE READING

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