Improvement in iron status and liver function in patients with transfusional iron overload with long-term subcutaneous desferrioxamine.

@article{Hoffbrand1979ImprovementII,
  title={Improvement in iron status and liver function in patients with transfusional iron overload with long-term subcutaneous desferrioxamine.},
  author={Allan Victor Hoffbrand and Annalisa Gorman and M. Laulicht and M Garidi and J C Economidou and P Georgipoulou and M. Arshad Hussain and D. Mickey Flynn},
  journal={Lancet},
  year={1979},
  volume={1 8123},
  pages={947-9}
}
Subcutaneous desferrioxamine (2--4 g over 12 h) was administered 6 nights each week to 34 patients with transfusional iron overloads who continued to receive regular blood-transfusions. All 34 patients showed a fall in serum-ferritin after 5 to 12 months. In some patients serum-ferritin fell almost to normal. Liver function improved in all the patients… CONTINUE READING