Improvement in human decay accelerating factor transgenic porcine kidney xenograft rejection with intravenous administration of gas914, a polymeric form of alphaGAL.

@article{Zhong2003ImprovementIH,
  title={Improvement in human decay accelerating factor transgenic porcine kidney xenograft rejection with intravenous administration of gas914, a polymeric form of alphaGAL.},
  author={Robert Z. Zhong and Yigang Luo and Hongji Yang and B. Bueno Garc{\'i}a and Anand Ghanekar and Patrick P Luke and Subrata Chakrabarti and Ginette Lajoie and Melville J Phillips and Andreas G Katopodis and Rudolf O. Duthaler and Mark S Cattral and W. Alan Wall and Anthony M Jevnikar and Michele Bailey and Gary A. Levy and David Grant},
  journal={Transplantation},
  year={2003},
  volume={75 1},
  pages={10-9}
}
BACKGROUND The present study was undertaken to determine whether intravenous administration of GAS914, a polymeric form of alphaGal, would minimize porcine kidney xenograft rejection in baboons. Human decay accelerating factor renal xenografts were transplanted into 16 baboon recipients. METHODS Baseline immunosuppression for all groups included cyclosporine A, cyclophosphamide, SDZ-RAD, and methylprednisolone. Group 1 received only baseline immunosuppression; group 2 animals received low… CONTINUE READING
11 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…