Improved whole-chromosome phasing for disease and population genetic studies

@article{Delaneau2012ImprovedWP,
  title={Improved whole-chromosome phasing for disease and population genetic studies},
  author={Olivier Delaneau and Jean-François Zagury and Jonathan Marchini},
  journal={Nature Methods},
  year={2012},
  volume={10},
  pages={5-6}
}
SHAPEIT2 uses multithreading so that multiple cores can be used to phase whole chromosomes, allowing users to make the best use of their computational resources. We tested SHAPEIT2 on several large-sample, whole-chromosome data sets from a range of SNP genotyping chips (Supplementary Note 1). SHAPEIT2 outperforms other methods (Fig. 1a–c) in terms of switch… CONTINUE READING

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