Improved viability of random pattern skin flaps through the use of adipose-derived stem cells.

@article{Lu2008ImprovedVO,
  title={Improved viability of random pattern skin flaps through the use of adipose-derived stem cells.},
  author={Feng Lu and Hiroshi Mizuno and Cagri Uysal and Xiaobo Cai and Rei Ogawa and Hiko Hyakusoku},
  journal={Plastic and reconstructive surgery},
  year={2008},
  volume={121 1},
  pages={50-8}
}
BACKGROUND Flap necrosis caused by inadequate blood supply is a common postoperative complication in reconstructive surgery. Because a putative stem cell population within the adipose tissue has been found to possess angiogenic potential, the authors sought to determine whether these cells might selectively induce neovascularization and increase the viability of random pattern skin flaps. METHODS Adipose-derived stem cells were isolated from the inguinal fat pads of ICR mice and expanded ex… CONTINUE READING

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