Improved sensitivity of the urine CAA lateral-flow assay for diagnosing active Schistosoma infections by using larger sample volumes

@inproceedings{Corstjens2015ImprovedSO,
  title={Improved sensitivity of the urine CAA lateral-flow assay for diagnosing active Schistosoma infections by using larger sample volumes},
  author={Paul L. A. M. Corstjens and Ruth K Nyakundi and Claudia J. de Dood and Thomas M. Kariuki and Elizabeth A. Ochola and Diana M S Karanja and Pauline N M Mwinzi and Govert J van Dam},
  booktitle={Parasites & Vectors},
  year={2015}
}
Accurate determination of Schistosoma infection rates in low endemic regions to examine progress towards interruption of transmission and elimination requires highly sensitive diagnostic tools. An existing lateral flow (LF) based test demonstrating ongoing infections through detection of worm circulating anodic antigen (CAA), was improved for sensitivity through implementation of a protocol allowing increased sample input. Urine is the preferred sample as collection is non-invasive and sample… CONTINUE READING
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Tjon Kon Fat EM , Wilson RA , Kariuki TM , et al . Tools for diagnosis , monitoring and screening of Schistosoma infections utilizing lateral - flow based assays and upconverting phosphor labels

  • PL Corstjens, CJ deDood, D Kornelis
  • Parasitology
  • 2014

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