• Engineering
  • Published 2016

Improved seed train strategy applied to PER.C6® cells for manufacturing readiness in vaccines production

@inproceedings{Nestola2016ImprovedST,
  title={Improved seed train strategy applied to PER.C6® cells for manufacturing readiness in vaccines production},
  author={Piergiuseppe Nestola and Sabine Kuratli and Claudio Thomasin},
  year={2016}
}
The recent Ebola virus outbreak has challenged the vaccine industry to boost the speed to market and process development activities for new vaccines. To be able to cope with infectious disease outbreaks, our company developed an intensified cell and virus culture process using PER.C6 cells and AdVacTM platform. In our intensified process, perfusion bioreactors are used to increase Adeno vector titers while minimizing capital investments. To further increase readiness and flexibility for… CONTINUE READING