Improved screening test for abnormal hemoglobins from dried blood samples

@article{Altland1979ImprovedST,
  title={Improved screening test for abnormal hemoglobins from dried blood samples},
  author={Klaus Altland and M. Kaempfer and Hilda Granda},
  journal={Human Genetics},
  year={1979},
  volume={53},
  pages={97-100}
}
A method is described wherin blood samples taken from adults or newborns and dried on filter paper can be used for hemoglobin analysis within 2 years after sampling. The samples are eluted in 8 M urea in the presence of 5% 2-mercaptoethanol and 2% of the neutral detergent Nonidet P-40. Then the individual α, β, γ, and δ chains are separated by means of electrofocusing in 8 M urea-PAA gels. Up to 96 samples can be applied to a gel using multiple syringes. Several hundred samples can be analyzed… CONTINUE READING
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Screening for abnormal hemoglobins in the newborn: A highly economic procedure using isoelectric focusing

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2 Excerpts

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2 Excerpts

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