Improved reflexive testing algorithm for hepatitis C infection using signal-to-cutoff ratios of a hepatitis C virus antibody assay.

@article{Lai2011ImprovedRT,
  title={Improved reflexive testing algorithm for hepatitis C infection using signal-to-cutoff ratios of a hepatitis C virus antibody assay.},
  author={Keane K Y Lai and Ming Jin and Shan Yuan and Meaghan F. Larson and Jason A. Dominitz and Daniel D. Bankson},
  journal={Clinical chemistry},
  year={2011},
  volume={57 7},
  pages={1050-6}
}
BACKGROUND Chemiluminescence immunoassay (CIA) is used to detect hepatitis C virus (HCV) antibody status on the basis of signal-to-cutoff (S/Co) ratios. Positive results of antibody to HCV (anti-HCV) are followed by either recombinant immunoblot assay (RIBA) to confirm anti-HCV positivity or reverse transcription (RT)-PCR to detect viremia. We hypothesized… CONTINUE READING