Improved quantification in multiple-pinhole SPECT by anatomy-based reconstruction using microCT information

@article{Vanhove2010ImprovedQI,
  title={Improved quantification in multiple-pinhole SPECT by anatomy-based reconstruction using microCT information},
  author={Christian Vanhove and Michel Defrise and Axel Bossuyt and Tony Lahoutte},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
  year={2010},
  volume={38},
  pages={153-165}
}
The aim of this study was to evaluate the potential of anatomy-based reconstruction, using microCT information, to improve quantitative accuracy in multiple-pinhole SPECT. Multiple-pinhole SPECT and microCT images were acquired with the Micro Deluxe Phantom using both hot and cold rod inserts. The phantoms were filled with 3.7 MBq/ml of 99mTc. To improve microCT contrast, the phantoms were also filled with contrast agent. Emission images were reconstructed using a one-step-late (OSL… CONTINUE READING