Improved protocol for treatment of pemphigus vulgaris with protein A immunoadsorption.

@article{Shimanovich2006ImprovedPF,
  title={Improved protocol for treatment of pemphigus vulgaris with protein A immunoadsorption.},
  author={Iakov Shimanovich and Susanne Herzog and Enno Schmidt and Andreas Opitz and Erdmute Klinker and E Br{\"o}cker and Matthias Goebeler and Detlev Zillikens},
  journal={Clinical and experimental dermatology},
  year={2006},
  volume={31 6},
  pages={768-74}
}
BACKGROUND Pemphigus vulgaris is a life-threatening autoimmune blistering skin disease, usually treated with high-dose corticosteroids in combination with other immunosuppressants. However, this regimen may prove inadequate in severe cases and can cause dangerous side-effects. We have recently reported protein A immunoadsorption (PAIA) to be an effective adjuvant treatment for induction of remission in severe pemphigus. However, in a significant number of cases, the disease rapidly recurred… CONTINUE READING

Similar Papers

Loading similar papers…