Improved precision and accuracy for microarrays using updated probe set definitions

@article{Sandberg2006ImprovedPA,
  title={Improved precision and accuracy for microarrays using updated probe set definitions},
  author={Rickard Sandberg and Ola Larsson},
  journal={BMC Bioinformatics},
  year={2006},
  volume={8},
  pages={48 - 48}
}
Microarrays enable high throughput detection of transcript expression levels. Different investigators have recently introduced updated probe set definitions to more accurately map probes to our current knowledge of genes and transcripts. We demonstrate that updated probe set definitions provide both better precision and accuracy in probe set estimates compared to the original Affymetrix definitions. We show that the improved precision mainly depends on the increased number of probes that are… CONTINUE READING
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