Improved plasma removal efficiency for therapeutic plasma exchange using a new apheresis platform.

@article{Tormey2010ImprovedPR,
  title={Improved plasma removal efficiency for therapeutic plasma exchange using a new apheresis platform.},
  author={Christopher A Tormey and Marie E Peddinghaus and Michelle Erickson and Karen E. King and Melissa M Cushing and Jerry Bill and Tay Goodrich and Edward L. Snyder},
  journal={Transfusion},
  year={2010},
  volume={50 2},
  pages={471-7}
}
BACKGROUND The Spectra Optia (SPO; CaridianBCT) is a new apheresis device based on the COBE Spectra (CSP; CaridianBCT) platform. This study was designed to evaluate the safety and efficiency of the SPO in comparison to the predicate CSP device. STUDY DESIGN AND METHODS Twenty patients were recruited for a randomized, nonblinded, paired (crossover) clinical trial comparing the SPO to the CSP (pivotal trial). The primary outcome measure was plasma removal efficiency (PRE); secondary outcomes… CONTINUE READING