Improved performance of first-trimester combined screening for trisomy 21 with the double test taken before a gestational age of 10 weeks.

@article{Kirkegaard2008ImprovedPO,
  title={Improved performance of first-trimester combined screening for trisomy 21 with the double test taken before a gestational age of 10 weeks.},
  author={Ida Kirkegaard and Olav Bj\orn Petersen and Niels Uldbjerg and Niels T\orring},
  journal={Prenatal diagnosis},
  year={2008},
  volume={28 9},
  pages={839-44}
}
OBJECTIVE To evaluate if there is a performance difference in the combined screening for trisomy 21 between the double tests performed before and after 10 + 0 weeks of gestation. METHODS The study included all 97 trisomy 21 cases from January 2004 to December 2007, in a screening program where the double test was measured in week 8 + 0 to 13 + 6 and the nuchal translucency in week 11 + 3 to 13 + 6. RESULTS As many as 87 of the 97 cases were diagnosed in the screening program (detection rate… CONTINUE READING

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