Improved performance characteristics of the von Willebrand factor ristocetin cofactor activity assay using a novel automated assay protocol.

@article{Hillarp2010ImprovedPC,
  title={Improved performance characteristics of the von Willebrand factor ristocetin cofactor activity assay using a novel automated assay protocol.},
  author={Andreas Hillarp and Maria Stadler and C Haderer and Josef Weinberger and Craig Kessler and Juergen R Roemisch},
  journal={Journal of thrombosis and haemostasis : JTH},
  year={2010},
  volume={8 10},
  pages={2216-23}
}
UNLABELLED BACKGROUND, OBJECTIVES AND METHODS: An accurate, sensitive and precise assay for reliable determination of the ristocetin cofactor activity of von Willebrand factor (VWF:RCo) in plasma and von Willebrand Factor (VWF)-containing concentrates has been evaluated. The assay is based on a commercially available automated protocol with modifications including a combination of adding additional ristocetin and the use of two calibration curves for the high and low measuring ranges. RESULTS… CONTINUE READING
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