Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of patients with mixed-lineage-leukemia-rearranged acute leukemia: Results from a prospective, multi-center study.

@article{Wang2014ImprovedOW,
  title={Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of patients with mixed-lineage-leukemia-rearranged acute leukemia: Results from a prospective, multi-center study.},
  author={Yu Wang and Qifa Liu and Ya-zhen Qin and Dai-Hong Liu and Lanping Xu and Bin Jiang and Qian Jiang and Min Dai and Si-Jian Yu and X Jiang and Yan-rong Liu and Xiaojun Huang},
  journal={American journal of hematology},
  year={2014},
  volume={89 2},
  pages={130-6}
}
The purpose of this study is to define the role for allogeneic hematopoietic stem cell transplantation (allo-HSCT) in mixed-lineage-leukemia (MLL)-rearranged acute leukemia, which is now poorly understood. A prospective, multi-center cohort study to determine whether allo-HSCT could decrease relapse rates and improve long-term survival of MLL+ leukemia patients was performed. Fifty-six consecutive patients diagnosed with MLL-rearranged acute leukemia undergoing allo-HSCT from two transplant… CONTINUE READING

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