Improved outcome of clindamycin compared with beta-lactam antibiotic treatment for invasive Streptococcus pyogenes infection.


CONTEXT Animal model studies have demonstrated the failure of penicillin to cure Streptococcus pyogenes myositis and have suggested that clindamycin is a more effective treatment. OBJECTIVE To determine the most effective antibiotic treatment for invasive S. pyogenes infection in humans. DESIGN AND SETTING We conducted a retrospective review of the… (More)


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