Improved outcome of APACHE II score-defined escalating systemic inflammatory response syndrome in patients post cardiac surgery in 1996 compared to 1988-1990: the ESSICS-study pilot project.

@article{Kuhn2000ImprovedOO,
  title={Improved outcome of APACHE II score-defined escalating systemic inflammatory response syndrome in patients post cardiac surgery in 1996 compared to 1988-1990: the ESSICS-study pilot project.},
  author={Christian Kuhn and Ursula Mueller-Werdan and Dierk V. Schmitt and Heike Lange and G{\"u}nter Pilz and Eckart Kreuzer and Friedrich W. Mohr and Hans Reinhard Zerkowski and Karl Werdan},
  journal={European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery},
  year={2000},
  volume={17 1},
  pages={
          30-7
        }
}
OBJECTIVE Cardiac surgery using extracorporeal circulation leads to the release of cytokines and subsequently to a systemic inflammatory response syndrome, which is thought to be a negative prognostic factor for patients' outcome. A stratification for the risk of an escalating systemic inflammatory response syndrome had been achieved in a monocenter study carried out in 1988-1990, using APACHE II scoring on the morning of the 1st postoperative day. We now re-evaluated this concept prospectively… CONTINUE READING

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