Improved motor function in dko mice by intravenous transplantation of bone marrow-derived mesenchymal stromal cells.

Abstract

BACKGROUND AIMS We explored the potential therapeutic value of transplanting bone marrow (BM)-derived mesenchymal stromal cells (MSC) into utrophin/dystrophin-deficient double knock-out (dko) mice, a murine model of Duchenne muscular dystrophy. METHODS MSC from male rats were isolated and transplanted into female dko mice via the caudal vein. Behavior and… (More)
DOI: 10.3109/14653249.2010.510502

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