Improved molecular classification of serrated lesions of the colon by immunohistochemical detection of BRAF V600E

@article{Mesteri2014ImprovedMC,
  title={Improved molecular classification of serrated lesions of the colon by immunohistochemical detection of BRAF V600E},
  author={Ildiko Mesteri and Guenther Bayer and Jochen Meyer and David R. Capper and Sebastian F Schoppmann and Andreas von Deimling and Peter Birner},
  journal={Modern Pathology},
  year={2014},
  volume={27},
  pages={135-144}
}
BRAF V600E mutation in serrated lesions of the colon has been implicated as an important mutation and as a specific marker for the serrated carcinogenic pathway. Recent findings point to microvesicular hyperplastic polyps that have similar histologic and molecular features to sessile serrated adenomas/polyps, as potential colorectal carcinoma precursors. The aim of this study was to evaluate BRAF V600E mutation status by immunohistochemistry in serrated lesions of the colon with regard to… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

Targeting BRAF Mutations in High-Grade Neuroendocrine Carcinoma of the Colon.

Journal of the National Comprehensive Cancer Network : JNCCN • 2018

Long-Term Impact of the Dutch Colorectal Cancer Screening Program on Cancer Incidence and Mortality-Model-Based Exploration of the Serrated Pathway.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology • 2016
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 38 references

Similar Papers

Loading similar papers…