Corpus ID: 41739604

Improved method for measuring C1-r-C1-s-(C1 inh)2 complexes by an enzyme-linked immunosorbent assay.

@article{Mathews1995ImprovedMF,
  title={Improved method for measuring C1-r-C1-s-(C1 inh)2 complexes by an enzyme-linked immunosorbent assay.},
  author={K. Mathews and J. Herschbach and S. L. Chambers and B. Zuraw},
  journal={Journal of clinical laboratory analysis},
  year={1995},
  volume={9 3},
  pages={
          196-203
        }
}
Measurement of C1-r-C1-s-(C1 inh)2 complexes in serum or plasma by enzyme-linked immunosorbent assay (ELISA) has been proposed as a relatively convenient and sensitive means for assessing C1 activation. However, interference by unactivated C1q (r-s)2 at low serum or plasma dilutions has resulted in estimates that vary widely with the degree of serum or plasma dilution. Precipitating the interfering C1q (r-s)2 with 6% polyethylene glycol has been proposed to resolve this problem, but here it is… Expand