Improved metabolic control in patients with non-insulin-dependent diabetes mellitus is associated with a slower accumulation of glycation products in collagen.

@article{Salmela1995ImprovedMC,
  title={Improved metabolic control in patients with non-insulin-dependent diabetes mellitus is associated with a slower accumulation of glycation products in collagen.},
  author={Pasi I. Salmela and Aarne Oikarinen and Olavi H Ukkola and Ari Karjalainen and Markku Linnaluoto and Raija Puukka and Lasse Ryh{\"a}nen},
  journal={European journal of clinical investigation},
  year={1995},
  volume={25 7},
  pages={494-500}
}
Twenty-one patients with non-insulin-dependent diabetes in poor metabolic control were subjected to intensified therapy, in most cases with insulin, to investigate whether it is possible to slow down the accumulation of advanced glycosylation end products of collagen by improving glycaemic control. Fasting and mean daily blood glucose, serum fructosamine and glycohaemoglobin levels, as well as glycation of collagen were measured before and after 1.5 years of intensified therapy. All these… CONTINUE READING

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Twenty - one patients with non - insulin - dependent diabetes in poor metabolic control were subjected to intensified therapy , in most cases with insulin , to investigate whether it is possible to slow down the accumulation of advanced glycosylation end products of collagen by improving glycaemic control .
Twenty - one patients with non - insulin - dependent diabetes in poor metabolic control were subjected to intensified therapy , in most cases with insulin , to investigate whether it is possible to slow down the accumulation of advanced glycosylation end products of collagen by improving glycaemic control .
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