Improved insecticidal efficacy of a recombinant baculovirus expressing mutated JH esterase from Manduca sexta

@inproceedings{ElSheikh2011ImprovedIE,
  title={Improved insecticidal efficacy of a recombinant baculovirus expressing mutated JH esterase from Manduca sexta},
  author={El-Sayed Abdel-Malek El-Sheikh and Shizuo George Kamita and Kiem Vu and Bruce D Hammock},
  year={2011}
}
Abstract Juvenile hormone esterase (JHE), a member of the carboxylesterase family (EC 3.1.1.1), metabolizes JH that is found in juvenile insects. A highly conserved amphipathic alpha helix is found on the surface of known JHEs. This helix is implicated in receptor-mediated binding and endocytosis of JHE by the pericardial cells resulting in the clearance of JHE activity from the hemolymph. In this study, Lys-204 and Arg-208 of the amphipathic alpha helix of the JHE of Manduca sexta (MsJHE) were… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 40 REFERENCES

Baculovirus expression systems and insect cells.

  • Bioprocess technology
  • 1991
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Juvenile hormone (JH) esterase: why are you so JH specific?

  • Insect biochemistry and molecular biology
  • 2003
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

ViStat: statistical package for the analysis of baculovirus bioassay data: version 2.1. Boyce Thompson Institute at Cornell University, Ithaca

P. R. Hughes
  • 1990
VIEW 1 EXCERPT
HIGHLY INFLUENTIAL