Improved in vitro digestion stability of (-)-epigallocatechin gallate through nanoliposome encapsulation.

  title={Improved in vitro digestion stability of (-)-epigallocatechin gallate through nanoliposome encapsulation.},
  author={Li-qiang Zou and Sheng-feng Peng and Wei Liu and Lu Gan and Wei-lin Liu and Rui-hong Liang and Cheng Liu and Jing Niu and Yan-Lin Cao and Zhen Liu and Xing Chen},
  journal={Food research international},
(-)-Epigallocatechin gallate (EGCG) is unstable and degraded in near-neutral or alkaline fluids. To overcome its limitation, EGCG nanoliposome (EN) was prepared by an ethanol injection method combined with dynamic high-pressure microfluidization. EN possessed good physicochemical characterizations (high entrapment efficiency=92.1%, small average particle size=71.7nm, low polydispersity index=0.286 and zeta potential=-10.81mv). EN exhibited a relative good sustained release property. Stability… CONTINUE READING


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