Improved high-performance liquid chromatographic method for simultaneous determination of 12 cytotoxic caged xanthones in gamboges, a potential anticancer resin from Garcinia hanburyi.

@article{Li2008ImprovedHL,
  title={Improved high-performance liquid chromatographic method for simultaneous determination of 12 cytotoxic caged xanthones in gamboges, a potential anticancer resin from Garcinia hanburyi.},
  author={Song-Lin Li and Jing-zheng Song and Quanbin Han and Chun-feng Qiao and Hong-xi Xu},
  journal={Biomedical chromatography : BMC},
  year={2008},
  volume={22 6},
  pages={
          637-44
        }
}
The potential anti-tumor activity of gamboges, a herbal medicine derived from Garcinia hanburyi, has increasingly gained the interest of scientist worldwide. The major components of gamboges are cytotoxic caged xanthones. In the present study, an improved HPLC method was developed to simultaneously quantify 12 caged xanthones, including three pairs of epimers and four pairs of trans-cis isomers, i.e. forbesione, isomorellic acid, morellic acid, R-30-hydroxygambogic acid, S-30-hydroxygambogic… CONTINUE READING

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Caged Garcinia Xanthones : Development Since 1937

Q.-B. Han, H.-X. Xu
  • 2009
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