Improved health-related quality of life following a randomized controlled trial of alefacept treatment in patients with chronic plaque psoriasis.

@article{Feldman2004ImprovedHQ,
  title={Improved health-related quality of life following a randomized controlled trial of alefacept treatment in patients with chronic plaque psoriasis.},
  author={Steven R. Feldman and Alexander Menter and John Y. M. Koo},
  journal={The British journal of dermatology},
  year={2004},
  volume={150 2},
  pages={
          317-26
        }
}
BACKGROUND Psoriasis has a negative impact on patients' quality of life. Treatment strategies should address both the cutaneous manifestations of the disease and their impact on quality of life. OBJECTIVES To evaluate the effect of alefacept on quality of life in 553 patients with chronic plaque psoriasis. METHODS In this multicentre, double-blind, parallel-groups study, patients were randomized to receive alefacept for two courses, alefacept in course 1 and placebo in course 2, or placebo… CONTINUE READING

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