Improved health outcomes in patients with COPD during 1 yr's treatment with tiotropium.

  title={Improved health outcomes in patients with COPD during 1 yr's treatment with tiotropium.},
  author={Walter Vincken and Jan A van Noord and A. P. M. Greefhorst and Th A Bantje and Steven Kesten and Lawrence Korducki and Piet J. G. Cornelissen},
  journal={The European respiratory journal},
  volume={19 2},
Tiotropium, a novel once-daily inhaled anticholinergic, has been shown to improve lung function over a 24-h period. In order to extend these findings, health-outcomes were evaluated over 1 yr in chronic obstructive pulmonary disease (COPD) patients. Spirometric results, peak expiratory flow rate (PEFR), salbutamol use and effects on dyspnoea, health-related quality of life and COPD exacerbations were assessed in two identical 1-yr randomized double-blind double-dummy studies of tiotropium 18… CONTINUE READING
Highly Influential
This paper has highly influenced 16 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 254 extracted citations

Safety, tolerability and risk benefit analysis of tiotropium in COPD

International journal of chronic obstructive pulmonary disease • 2008
View 6 Excerpts
Highly Influenced

Tiotropium Bromide

View 10 Excerpts
Highly Influenced

Tiotropium in the management of chronic obstructive pulmonary disease.

The European respiratory journal • 2002
View 5 Excerpts
Highly Influenced

Bronchodilation of umeclidinium, a new long-acting muscarinic antagonist, in COPD patients.

Respiratory physiology & neurobiology • 2013
View 2 Excerpts
Highly Influenced

Tiotropium Bromide Inhalation Powder

Drugs • 2012
View 8 Excerpts
Highly Influenced

Effect of tiotropium on quality of life in COPD: a systematic review.

Primary care respiratory journal : journal of the General Practice Airways Group • 2010
View 3 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 26 references

The measurement of dyspnea: contents, interobserver agreement, and physiologic correlates of two new clinical indexes

DA Mahler, DH Weinber, CK Wells, AR. Feinstein
Chest • 1984
View 9 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…